Immunoreactive calmodulin in supernatant fraction of platelet homogenates from humans, guinea pigs, rats, and rabbits

Immunoreactive calmodulin in supernatant fraction of platelet homogenates from humans, guinea pigs, rats, and rabbits

Abstract Immunoreactive Calmodulin (CM) was measured in the supernatant fraction of homogenates of platelets obtained from humans, rats, guinea pigs and rabbits, using a commercial RIA kit. The levels (μg/g wet weight of platelets) of immunoreactive CM were 6.8 ± 0.5, 6.9 ± 0.4, 8.6 ± 1.8 and 9.7 ±...

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Veröffentlicht in:Archives internationales de physiologie et de biochimie 1984-01, Vol.92 (2), p.85-88
Hauptverfasser: Levy, J. V., Trinh, D.
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Animals
Blood Platelets - analysis
Calmodulin - blood
Guinea Pigs
Humans
Male
Rabbits
Radioimmunoassay
Rats
Rats, Inbred Strains
Species Specificity
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Zusammenfassung:Abstract Immunoreactive Calmodulin (CM) was measured in the supernatant fraction of homogenates of platelets obtained from humans, rats, guinea pigs and rabbits, using a commercial RIA kit. The levels (μg/g wet weight of platelets) of immunoreactive CM were 6.8 ± 0.5, 6.9 ± 0.4, 8.6 ± 1.8 and 9.7 ± 3.1 (mean ± SEM) for rat, human, rabbit and guinea pig, respectively. There was no statistically significant difference in values between these four species. The refractoriness of rat platelets to aggregate to certain agonists such as platelet activating factor (PAF) cannot be explained on differences in amount of immunoreactive CM.
ISSN:1381-3455
0003-9799
1744-4160
DOI:10.3109/13813458409071131