The Formation of Photoreactivable Damage by Direct Excitation of DNA in X-irradiated E. Coli Cells

The Formation of Photoreactivable Damage by Direct Excitation of DNA in X-irradiated E. Coli Cells

Summary The role of the direct excitation process in the formation of photoreactivable damage (pyrimidine dimers) in E. coli WP2 hcr−exr− cells has been studied. The pyrimidine dimers were detected by photoreactivation following anoxic irradiation by X-rays (220 kVp). The dose modifying factor (DMF)...

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Veröffentlicht in:International journal of radiation biology 1985, Vol.47 (1), p.49-56
Hauptverfasser: Duba, V.V., Pitkevich, V.A., Selyova, N.G., Petrova, I.V., Myasnik, M.N.
Format: Artikel
Sprache:eng
Schlagworte:
DNA Repair
DNA, Bacterial - radiation effects
Escherichia coli - radiation effects
Light
Mathematics
Models, Biological
Radiation Genetics
Ultraviolet Rays
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Zusammenfassung:Summary The role of the direct excitation process in the formation of photoreactivable damage (pyrimidine dimers) in E. coli WP2 hcr−exr− cells has been studied. The pyrimidine dimers were detected by photoreactivation following anoxic irradiation by X-rays (220 kVp). The dose modifying factor (DMF) is 1·28 ± 0·09. A biophysical model is used for a theoretical examination of the importance of the direct excitation process in the formation of photoreactivable damage and the experimental data are consistent with this model.
ISSN:0955-3002
0020-7616
1362-3095
DOI:10.1080/09553008514550071