Modification of the Effect of Ultra-violet Irradiation by a Nutritive Condition on the Induced Formation of Catechol Oxygenase in Pseudomonas Effusa

Summary (1) The effect of ultra-violet radiation on the induced synthesis of catechol oxygenase was very different according to nutritive conditions of Pseudomonas effusa. (2) Significant damage to catechol-oxygenase synthesis depending on translation was observed under the enriched condition, whereas it was not affected under the deficient condition, by a dose sufficient to block induction. (3) From comparison of inhibiting modes, it is concluded that u.v.-irradiation under the enriched condition has an inhibitory effect on both transcription and translation. Under the deficient condition, a preferential damage on transcription is observed, whereas translation is not affected.