X-radiation and 5-hydroxytryptamine-content in the Brain of Rats and Mice
Summary Whole-body x-irradiation with high doses produces an increase in the 5-hydroxytryptamine-content in the brain of normal rats and mice. This effect was obtained with smaller doses only in adrenalectomized rats. Shielding of the head or body did not suppress this phenomenon. The same holds tru...
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| Veröffentlicht in: | Intern. J. Radiation Biol 1963-01, Vol.6 (3), p.241-246 |
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| container_title | Intern. J. Radiation Biol |
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| creator | Palai, Dj Randi, M. Supek, Z. |
| description | Summary
Whole-body x-irradiation with high doses produces an increase in the 5-hydroxytryptamine-content in the brain of normal rats and mice. This effect was obtained with smaller doses only in adrenalectomized rats. Shielding of the head or body did not suppress this phenomenon. The same holds true of pre-treatment with iproniazid or reserpine. |
| doi_str_mv | 10.1080/09553006314550311 |
| format | Article |
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Whole-body x-irradiation with high doses produces an increase in the 5-hydroxytryptamine-content in the brain of normal rats and mice. This effect was obtained with smaller doses only in adrenalectomized rats. Shielding of the head or body did not suppress this phenomenon. The same holds true of pre-treatment with iproniazid or reserpine.</description><identifier>ISSN: 0955-3002</identifier><identifier>ISSN: 0020-7616</identifier><identifier>EISSN: 1362-3095</identifier><identifier>DOI: 10.1080/09553006314550311</identifier><identifier>PMID: 13941172</identifier><language>eng</language><publisher>England: Informa UK Ltd</publisher><subject>ADRENAL GLANDS ; ALKALOIDS ; AMINO ACIDS ; Animals ; BIOCHEMISTRY ; BIOLOGY AND MEDICINE ; BODY ; Brain ; DRUGS ; IPRONIAZID ; MICE ; RADIATION EFFECTS ; RATS ; RESERPINE ; SERINE ; Serotonin ; SHIELDING ; SURGERY ; X RADIATION ; X-Rays</subject><ispartof>Intern. J. Radiation Biol, 1963-01, Vol.6 (3), p.241-246</ispartof><rights>1963 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted 1963</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c431t-e9d40d0d9765156496162f81dfae220ed68222a9240477e9f79b0c4f6adef6773</citedby><cites>FETCH-LOGICAL-c431t-e9d40d0d9765156496162f81dfae220ed68222a9240477e9f79b0c4f6adef6773</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.tandfonline.com/doi/pdf/10.1080/09553006314550311$$EPDF$$P50$$Ginformahealthcare$$H</linktopdf><linktohtml>$$Uhttps://www.tandfonline.com/doi/full/10.1080/09553006314550311$$EHTML$$P50$$Ginformahealthcare$$H</linktohtml><link.rule.ids>314,780,784,885,27923,27924,61220,61255,61401,61436</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/13941172$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://www.osti.gov/biblio/4698109$$D View this record in Osti.gov$$Hfree_for_read</backlink></links><search><creatorcontrib>Palai, Dj</creatorcontrib><creatorcontrib>Randi, M.</creatorcontrib><creatorcontrib>Supek, Z.</creatorcontrib><creatorcontrib>Inst. "Ruder Boskovic," Zagreb</creatorcontrib><title>X-radiation and 5-hydroxytryptamine-content in the Brain of Rats and Mice</title><title>Intern. J. Radiation Biol</title><addtitle>Int J Radiat Biol Relat Stud Phys Chem Med</addtitle><description>Summary
Whole-body x-irradiation with high doses produces an increase in the 5-hydroxytryptamine-content in the brain of normal rats and mice. This effect was obtained with smaller doses only in adrenalectomized rats. Shielding of the head or body did not suppress this phenomenon. The same holds true of pre-treatment with iproniazid or reserpine.</description><subject>ADRENAL GLANDS</subject><subject>ALKALOIDS</subject><subject>AMINO ACIDS</subject><subject>Animals</subject><subject>BIOCHEMISTRY</subject><subject>BIOLOGY AND MEDICINE</subject><subject>BODY</subject><subject>Brain</subject><subject>DRUGS</subject><subject>IPRONIAZID</subject><subject>MICE</subject><subject>RADIATION EFFECTS</subject><subject>RATS</subject><subject>RESERPINE</subject><subject>SERINE</subject><subject>Serotonin</subject><subject>SHIELDING</subject><subject>SURGERY</subject><subject>X RADIATION</subject><subject>X-Rays</subject><issn>0955-3002</issn><issn>0020-7616</issn><issn>1362-3095</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1963</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kEtLw0AUhQdRbK3-ADcS3EfvPDLJ4EqLL6gIouAuTOdBpjSTMpmC-fdOTcGF4OoeuOc73HsQOsdwhaGCaxBFQQE4xawogGJ8gKaYcpLTtDlE090-aSATdNL3K0gKaHWMJpgKhnFJpuj5Mw9SOxld5zPpdVbkzaBD9zXEMGyibJ03uep8ND5mzmexMdldkEl1NnuTsf-BXpwyp-jIynVvzvZzhj4e7t_nT_ni9fF5frvIFaM45kZoBhq0KHmBC84Ex5zYCmsrDSFgNK8IIVIQBqwsjbClWIJilkttLC9LOkOXY27XR1f3ykWjmnShNyrWjIsKg0gmPJpU6Po-GFtvgmtlGGoM9a67-k93ibkYmc122Rr9S-zLSoab0eC87UIrGyPXsVEymHrVbYNPX_8T_w31PnnF</recordid><startdate>19630101</startdate><enddate>19630101</enddate><creator>Palai, Dj</creator><creator>Randi, M.</creator><creator>Supek, Z.</creator><general>Informa UK Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>OTOTI</scope></search><sort><creationdate>19630101</creationdate><title>X-radiation and 5-hydroxytryptamine-content in the Brain of Rats and Mice</title><author>Palai, Dj ; Randi, M. ; Supek, Z.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c431t-e9d40d0d9765156496162f81dfae220ed68222a9240477e9f79b0c4f6adef6773</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1963</creationdate><topic>ADRENAL GLANDS</topic><topic>ALKALOIDS</topic><topic>AMINO ACIDS</topic><topic>Animals</topic><topic>BIOCHEMISTRY</topic><topic>BIOLOGY AND MEDICINE</topic><topic>BODY</topic><topic>Brain</topic><topic>DRUGS</topic><topic>IPRONIAZID</topic><topic>MICE</topic><topic>RADIATION EFFECTS</topic><topic>RATS</topic><topic>RESERPINE</topic><topic>SERINE</topic><topic>Serotonin</topic><topic>SHIELDING</topic><topic>SURGERY</topic><topic>X RADIATION</topic><topic>X-Rays</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Palai, Dj</creatorcontrib><creatorcontrib>Randi, M.</creatorcontrib><creatorcontrib>Supek, Z.</creatorcontrib><creatorcontrib>Inst. "Ruder Boskovic," Zagreb</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>OSTI.GOV</collection><jtitle>Intern. J. Radiation Biol</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Palai, Dj</au><au>Randi, M.</au><au>Supek, Z.</au><aucorp>Inst. "Ruder Boskovic," Zagreb</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>X-radiation and 5-hydroxytryptamine-content in the Brain of Rats and Mice</atitle><jtitle>Intern. J. Radiation Biol</jtitle><addtitle>Int J Radiat Biol Relat Stud Phys Chem Med</addtitle><date>1963-01-01</date><risdate>1963</risdate><volume>6</volume><issue>3</issue><spage>241</spage><epage>246</epage><pages>241-246</pages><issn>0955-3002</issn><issn>0020-7616</issn><eissn>1362-3095</eissn><abstract>Summary
Whole-body x-irradiation with high doses produces an increase in the 5-hydroxytryptamine-content in the brain of normal rats and mice. This effect was obtained with smaller doses only in adrenalectomized rats. Shielding of the head or body did not suppress this phenomenon. The same holds true of pre-treatment with iproniazid or reserpine.</abstract><cop>England</cop><pub>Informa UK Ltd</pub><pmid>13941172</pmid><doi>10.1080/09553006314550311</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0955-3002 |
| ispartof | Intern. J. Radiation Biol, 1963-01, Vol.6 (3), p.241-246 |
| issn | 0955-3002 0020-7616 1362-3095 |
| language | eng |
| recordid | cdi_informahealthcare_journals_10_1080_09553006314550311 |
| source | MEDLINE; Taylor & Francis:Master (3349 titles); Taylor & Francis Medical Library - CRKN |
| subjects | ADRENAL GLANDS ALKALOIDS AMINO ACIDS Animals BIOCHEMISTRY BIOLOGY AND MEDICINE BODY Brain DRUGS IPRONIAZID MICE RADIATION EFFECTS RATS RESERPINE SERINE Serotonin SHIELDING SURGERY X RADIATION X-Rays |
| title | X-radiation and 5-hydroxytryptamine-content in the Brain of Rats and Mice |
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