X-radiation and 5-hydroxytryptamine-content in the Brain of Rats and Mice

X-radiation and 5-hydroxytryptamine-content in the Brain of Rats and Mice

Summary Whole-body x-irradiation with high doses produces an increase in the 5-hydroxytryptamine-content in the brain of normal rats and mice. This effect was obtained with smaller doses only in adrenalectomized rats. Shielding of the head or body did not suppress this phenomenon. The same holds tru...

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Veröffentlicht in:Intern. J. Radiation Biol 1963-01, Vol.6 (3), p.241-246
Hauptverfasser: Palai, Dj, Randi, M., Supek, Z.
Format: Artikel
Sprache:eng
Schlagworte:
ADRENAL GLANDS
ALKALOIDS
AMINO ACIDS
Animals
BIOCHEMISTRY
BIOLOGY AND MEDICINE
BODY
Brain
DRUGS
IPRONIAZID
MICE
RADIATION EFFECTS
RATS
RESERPINE
SERINE
Serotonin
SHIELDING
SURGERY
X RADIATION
X-Rays
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Zusammenfassung:Summary Whole-body x-irradiation with high doses produces an increase in the 5-hydroxytryptamine-content in the brain of normal rats and mice. This effect was obtained with smaller doses only in adrenalectomized rats. Shielding of the head or body did not suppress this phenomenon. The same holds true of pre-treatment with iproniazid or reserpine.
ISSN:0955-3002
0020-7616
1362-3095
DOI:10.1080/09553006314550311