Single-molecule imaging in solution with total internal reflection excitation
Summary form only given.The detection of individual single-chromophore molecules in aqueous solution, first demonstrated with picoliter-sized sample volumes, and soon after with femtoliter-sized volumes, has become routinely achievable. More recently, the imaging of individual single-chromophore mol...
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creator | Parker, W.C. Davis, L.M. Williams, J.G.K. Middendorf, L.R. Bashford, C.R. |
description | Summary form only given.The detection of individual single-chromophore molecules in aqueous solution, first demonstrated with picoliter-sized sample volumes, and soon after with femtoliter-sized volumes, has become routinely achievable. More recently, the imaging of individual single-chromophore molecules in very thin layers of aqueous solution, using epifluorescence and total internal reflection (TIR) microscopies has been reported. |
doi_str_mv | 10.1109/CLEO.2000.907311 |
format | Conference Proceeding |
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More recently, the imaging of individual single-chromophore molecules in very thin layers of aqueous solution, using epifluorescence and total internal reflection (TIR) microscopies has been reported.</description><identifier>ISBN: 1557526346</identifier><identifier>ISBN: 9781557526342</identifier><identifier>DOI: 10.1109/CLEO.2000.907311</identifier><language>eng</language><publisher>IEEE</publisher><subject>Bones ; Fiber lasers ; Laser ablation ; Laser excitation ; Laser surgery ; Optical control ; Optical reflection ; Optical scattering ; Proteins ; Surges</subject><ispartof>Conference on Lasers and Electro-Optics (CLEO 2000). Technical Digest. Postconference Edition. TOPS Vol.39 (IEEE Cat. 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TOPS Vol.39 (IEEE Cat. No.00CH37088)</title><addtitle>CLEO</addtitle><description>Summary form only given.The detection of individual single-chromophore molecules in aqueous solution, first demonstrated with picoliter-sized sample volumes, and soon after with femtoliter-sized volumes, has become routinely achievable. More recently, the imaging of individual single-chromophore molecules in very thin layers of aqueous solution, using epifluorescence and total internal reflection (TIR) microscopies has been reported.</description><subject>Bones</subject><subject>Fiber lasers</subject><subject>Laser ablation</subject><subject>Laser excitation</subject><subject>Laser surgery</subject><subject>Optical control</subject><subject>Optical reflection</subject><subject>Optical scattering</subject><subject>Proteins</subject><subject>Surges</subject><isbn>1557526346</isbn><isbn>9781557526342</isbn><fulltext>true</fulltext><rsrctype>conference_proceeding</rsrctype><creationdate>2000</creationdate><recordtype>conference_proceeding</recordtype><sourceid>6IE</sourceid><sourceid>RIE</sourceid><recordid>eNotT01PwzAUi4SQgLE74pQ_0PJe0iTtEVXjQyragd2nNHsZQVmL2kzAvycwTrZs2bIZu0EoEaG5a7vVuhQAUDZgJOIZu0KljBJaVvqCLef5PZugwACqS_byGoZ9pOIwRnLHSDwc7D5LPAx8HuMxhXHgnyG98TQmG7OcaBoymcjnxJ9NXy4k-0uv2bm3cablPy7Y5mG1aZ-Kbv343N53RahNKirjfAXe9V6T2XlqwJsedjWQ05Uj7bWgRqBC7aCSPaBptFCGLCisBUi5YLen2kBE248pb56-t6e_8gcdA0xn</recordid><startdate>2000</startdate><enddate>2000</enddate><creator>Parker, W.C.</creator><creator>Davis, L.M.</creator><creator>Williams, J.G.K.</creator><creator>Middendorf, L.R.</creator><creator>Bashford, C.R.</creator><general>IEEE</general><scope>6IE</scope><scope>6IH</scope><scope>CBEJK</scope><scope>RIE</scope><scope>RIO</scope></search><sort><creationdate>2000</creationdate><title>Single-molecule imaging in solution with total internal reflection excitation</title><author>Parker, W.C. ; Davis, L.M. ; Williams, J.G.K. ; Middendorf, L.R. ; Bashford, C.R.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-i87t-47cf40fcbf6e7dfe90f7b0d80ec64ce6f62e921516c043b01796257ea05182033</frbrgroupid><rsrctype>conference_proceedings</rsrctype><prefilter>conference_proceedings</prefilter><language>eng</language><creationdate>2000</creationdate><topic>Bones</topic><topic>Fiber lasers</topic><topic>Laser ablation</topic><topic>Laser excitation</topic><topic>Laser surgery</topic><topic>Optical control</topic><topic>Optical reflection</topic><topic>Optical scattering</topic><topic>Proteins</topic><topic>Surges</topic><toplevel>online_resources</toplevel><creatorcontrib>Parker, W.C.</creatorcontrib><creatorcontrib>Davis, L.M.</creatorcontrib><creatorcontrib>Williams, J.G.K.</creatorcontrib><creatorcontrib>Middendorf, L.R.</creatorcontrib><creatorcontrib>Bashford, C.R.</creatorcontrib><collection>IEEE Electronic Library (IEL) Conference Proceedings</collection><collection>IEEE Proceedings Order Plan (POP) 1998-present by volume</collection><collection>IEEE Xplore All Conference Proceedings</collection><collection>IEEE Electronic Library (IEL)</collection><collection>IEEE Proceedings Order Plans (POP) 1998-present</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Parker, W.C.</au><au>Davis, L.M.</au><au>Williams, J.G.K.</au><au>Middendorf, L.R.</au><au>Bashford, C.R.</au><format>book</format><genre>proceeding</genre><ristype>CONF</ristype><atitle>Single-molecule imaging in solution with total internal reflection excitation</atitle><btitle>Conference on Lasers and Electro-Optics (CLEO 2000). Technical Digest. Postconference Edition. TOPS Vol.39 (IEEE Cat. No.00CH37088)</btitle><stitle>CLEO</stitle><date>2000</date><risdate>2000</risdate><spage>502</spage><epage>503</epage><pages>502-503</pages><isbn>1557526346</isbn><isbn>9781557526342</isbn><abstract>Summary form only given.The detection of individual single-chromophore molecules in aqueous solution, first demonstrated with picoliter-sized sample volumes, and soon after with femtoliter-sized volumes, has become routinely achievable. More recently, the imaging of individual single-chromophore molecules in very thin layers of aqueous solution, using epifluorescence and total internal reflection (TIR) microscopies has been reported.</abstract><pub>IEEE</pub><doi>10.1109/CLEO.2000.907311</doi><tpages>2</tpages></addata></record> |
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subjects | Bones Fiber lasers Laser ablation Laser excitation Laser surgery Optical control Optical reflection Optical scattering Proteins Surges |
title | Single-molecule imaging in solution with total internal reflection excitation |
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