A Linear Formulation of Asynchronous Boolean Networks

A Linear Formulation of Asynchronous Boolean Networks

A new linear approach is proposed to model the dynamics of asynchronous Boolean networks (ABNs). The continuous-time discrete-state model definition makes the ABN a suitable formulation to describe gene regulatory networks. The semi-tensor product of matrices is used as the algebraic tool for the li...

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Veröffentlicht in:IEEE control systems letters 2019-04, Vol.3 (2), p.284-289
Hauptverfasser: Das, Haimabati, Deshpande, Anuj, Layek, Ritwik Kumar
Format: Artikel
Sprache:eng
Schlagworte:
Biological system modeling
Boolean functions
Computational modeling
Computational systems biology
Delays
Mathematical model
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Zusammenfassung:A new linear approach is proposed to model the dynamics of asynchronous Boolean networks (ABNs). The continuous-time discrete-state model definition makes the ABN a suitable formulation to describe gene regulatory networks. The semi-tensor product of matrices is used as the algebraic tool for the linear formulation. The results on the dynamics of the ABN are elaborated with synthetic and biological examples.
ISSN:2475-1456
2475-1456
DOI:10.1109/LCSYS.2018.2869045