Evaluating exponential integrators for Markov chain ion channel models

We evaluate the accuracy and efficiency of an exponential integrator method applied to a cardiac excitation model with numerically stiff Markov chain (MC) description of ionic channels, namely Ryanodine receptor (RyR) and L-type calcium channel ICa(L). If solved by explicit methods such as forward E...

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Bibliographische Detailangaben

Hauptverfasser:	Stary, Tomas, Biktashev, Vadim N.
Format:	Tagungsbericht
Sprache:	eng
Schlagworte:	Calcium Cardiology Channels Computation Computational modeling Conferences Integrators Ion channels Iron Logic gates Markov chains Markov processes Mathematical model Mathematical models Numerical models
Online-Zugang:	Volltext
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