Emergency life support system aiming preprimed oxygenator

Development have been achieved of a new blood pump for next generation Percutaneous Cardio-Pulmonary Support (PCPS) system and a novel surface coating method for silicone membrane hollow fiber by physical adsorption using a copolymer composed of a 2-Methacryloyloxyethyl phosphorylcholine (MPC) unit...

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Veröffentlicht in:2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) 2013-01, Vol.2013, p.5731-5734
Hauptverfasser: Isoyama, Takashi, Ariyoshi, Koki, Nii, Kyosuke, Saito, Itsuro, Fukunaga, Kazuyoshi, Inoue, Yusuke, Ono, Toshiya, Ishii, Kohei, Hara, Shintaro, Imachi, Kou, Takai, Madoka, Abe, Yusuke
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Sprache:eng
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Zusammenfassung:Development have been achieved of a new blood pump for next generation Percutaneous Cardio-Pulmonary Support (PCPS) system and a novel surface coating method for silicone membrane hollow fiber by physical adsorption using a copolymer composed of a 2-Methacryloyloxyethyl phosphorylcholine (MPC) unit and a hydrophobic unit. The new blood pump, named the Troidal Convolution Pump (TCP), is based on the principle of a cascade pump and perfused 5 L/min and 350 mmHg at 2450 rpm. The novel copolymer composed of 30% MPC unit and 3-(methacryloyloxy) propyltris (trimethylsiloxy) silane (MPTSSi) unit (PMMSi30) was the most suitable molecular design on a silicone surface. The PMMSi30 coated surface adsorbed 7.2 % as much protein a non-coated surface adsorbed.
ISSN:1094-687X
1557-170X
1558-4615
DOI:10.1109/EMBC.2013.6610852