Signal transduction on enzymes: the Effect of electromagnetic field stimuli on superoxide dismutase (SOD)

Signal transduction on enzymes: the Effect of electromagnetic field stimuli on superoxide dismutase (SOD)

Protein functions and characteristics can highly differ from physiological conditions in presence of chemical, mechanical or electromagnetic stimuli. In this work we provide a rigorous picture of electric field effects on proteins behavior investigating, at atomistic details, the possible ways in wh...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Marracino, P., Migliorati, M., Paffi, A., Liberti, M., Denzi, A., d'Inzeo, G., Apollonio, F.
Format: Tagungsbericht
Sprache:eng
Schlagworte:
Biological system modeling
Electric fields
Electromagnetic Fields
Microwave oscillators
Models, Molecular
Molecular Dynamics Simulation
Physiology
Proteins
Signal Transduction
Spectrogram
Superoxide Dismutase - chemistry
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Protein functions and characteristics can highly differ from physiological conditions in presence of chemical, mechanical or electromagnetic stimuli. In this work we provide a rigorous picture of electric field effects on proteins behavior investigating, at atomistic details, the possible ways in which an external signal can be transduced into biochemical effects. Results from molecular dynamics (MD) simulations of a single superoxidismutase (SOD) enzyme in presence of high exogenous alternate electric fields will be discussed.
ISSN:1094-687X
1557-170X
1558-4615
DOI:10.1109/EMBC.2012.6347282