High power facilities for electroporation of biological cells in pulsed magnetic fields

High power facilities for electroporation of biological cells in pulsed magnetic fields

High power pulsed generator for non-contact cell electroporation application in pulsed magnetic fields is presented. Finite element method analysis of the magnetic field and the analysis of the Jurkat T lymphoblasts electroporation experimental data are overviewed. The dependence of cell electropora...

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Bibliographische Detailangaben
Hauptverfasser: Grainys, A., Novickij, V., Novickij, J., Stirke, A., Kaseta, V.
Format: Tagungsbericht
Sprache:eng
Schlagworte:
Capacitors
Drug delivery
Electric fields
Generators
Magnetic fields
microcoil
non-contact electroporation
pulsed magnetic field generator
Thyristors
Windings
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Beschreibung
Zusammenfassung:High power pulsed generator for non-contact cell electroporation application in pulsed magnetic fields is presented. Finite element method analysis of the magnetic field and the analysis of the Jurkat T lymphoblasts electroporation experimental data are overviewed. The dependence of cell electroporation efficiency on the structure of the microcoil was acquired experimentally. Possible problems of the technique, further developments and result overview are discussed.
DOI:10.1109/MIKON.2012.6233623