Predicting KRAS-targeting MicroRNAs using in silico approach

MicroRNAs are small non-coding genes that regulate the expression of the protein-coding genes. As these microRNAs play a pivotal role in disease development, it is important for the bioinformaticians and geneticians to know the target genes. This research adopted in silico approach to predict the KR...

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Bibliographische Detailangaben
Hauptverfasser: Sim-Hui Tee, Sin-Liang Lim
Format: Tagungsbericht
Sprache:eng
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Zusammenfassung:MicroRNAs are small non-coding genes that regulate the expression of the protein-coding genes. As these microRNAs play a pivotal role in disease development, it is important for the bioinformaticians and geneticians to know the target genes. This research adopted in silico approach to predict the KRAS-targeting microRNAs. The computational results shed light on the type of microRNAs that gives rise to the development of diseases due to the misregulation of KRAS gene.
DOI:10.1109/CHUSER.2011.6163870