IVUS-based assessment of 3D morphology and virtual histology: Prediction of atherosclerotic plaque status and changes

Comprehensive analysis of coronary morphology, plaque composition, hemodynamics, and systemic cardiovascular biomarkers is hypothesized to allow prediction of plaque development. We report the status of a comprehensive project, in which baseline and follow-up intravascular ultrasound imaging of coronary arteries during routine coronary interventions serve as a source of quantitative data for development of a predictive classifier for determining plaque progression over the course of a year from baseline data.