EEG complexity drug-induced changes in disorders of consciousness: A preliminary report

The goal of this work is to investigate EEG (ElectroEncephaloGram) dynamics after drug intake in patients being in states of Disorders Of Consciousness (DOC) after brain injury. Four patients were involved in the study. All the patients exhibit cerebral lesions located in the same anatomical region....

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Hauptverfasser:	Valenza, G., Carboncini, M. C., Virgillito, A., Creatini, I., Bonfiglio, L., Rossi, B., Lanata, A., Scilingo, E. P.
Format:	Tagungsbericht
Sprache:	eng
Schlagworte:	Brain injuries Brain Injuries - complications Complexity theory Consciousness Disorders - diagnosis Consciousness Disorders - drug therapy Consciousness Disorders - etiology Drugs Electroencephalography Entropy Humans Indexes Spectral analysis
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Beschreibung
Zusammenfassung:	The goal of this work is to investigate EEG (ElectroEncephaloGram) dynamics after drug intake in patients being in states of Disorders Of Consciousness (DOC) after brain injury. Four patients were involved in the study. All the patients exhibit cerebral lesions located in the same anatomical region. Two nonlinear indexes, such as Lempel-Ziv Complexity (LZC) and Approximate Entropy (ApEn), along with power spectra, were calculated for EEG signals gathered from electrodes placed on both injured and non-injured regions. Experimental results show that after drug administration the two nonlinear indexes calculated from EEG taken from injured regions increase (p
ISSN:	1094-687X 1557-170X 1558-4615
DOI:	10.1109/IEMBS.2011.6090633