A CMOS Hall-Effect Sensor for the Characterization and Detection of Magnetic Nanoparticles for Biomedical Applications

A CMOS Hall-Effect Sensor for the Characterization and Detection of Magnetic Nanoparticles for Biomedical Applications

A CMOS Hall-effect sensor chip designed for the characterization and detection of magnetic nanoparticles (MNPs) achieves over three orders of magnitude better temporal resolution than prior solutions based on superconducting quantum interference devices and fluxgate sensors. The sensor relies on wir...

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Veröffentlicht in:IEEE transactions on magnetics 2011-10, Vol.47 (10), p.3449-3451
Hauptverfasser: Liu, Paul, Skucha, Karl, Megens, Mischa, Boser, Bernhard
Format: Artikel
Sprache:eng
Schlagworte:
Anisotropic magnetoresistance
Biosensor
CMOS
CMOS integrated circuits
Cross-disciplinary physics: materials science
rheology
Exact sciences and technology
Hall-effect devices
Magnetic moments
magnetic nanoparticles (MNPs)
magnetic relaxation
Magnetometers
Materials science
Other topics in materials science
Perpendicular magnetic anisotropy
Physics
Superconducting magnets
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Beschreibung
Zusammenfassung:A CMOS Hall-effect sensor chip designed for the characterization and detection of magnetic nanoparticles (MNPs) achieves over three orders of magnitude better temporal resolution than prior solutions based on superconducting quantum interference devices and fluxgate sensors. The sensor relies on wires embedded in the chip to generate a local magnetizing field that is switched OFF rapidly to observe the relaxation field of the MNPs. The CMOS sensor chip, with integrated high-speed readout electronics, occupies 6.25 mm 2 . It can be easily integrated with microfluidics and is suitable for lab-on-a-chip and point-of-care applications.
ISSN:0018-9464
1941-0069
DOI:10.1109/TMAG.2011.2158600