Double Tilted Fiber Bragg Grating for label-free DNA detection

Double Tilted Fiber Bragg Grating for label-free DNA detection

We present a new approach for developing a label-free biosensor for detection of DNA. The biosensor based on a biofunctionalized Double Tilt Fiber Bragg Grating transduces the presence of DNA into a change of visibility of fringes of its interference spectrum. Real-time spectral measurement results...

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Hauptverfasser: Candiani, A., Sozzi, M., Coscelli, E., Poli, F., Cucinotta, A., Selleri, S., Veneziano, R., Corradini, R., Marchelli, R., Childs, P., Pissadakis, S.
Format: Tagungsbericht
Sprache:eng
Schlagworte:
Biosensors
Bragg gratings
DNA
Optical fiber sensors
Optical fibers
Refractive index
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Beschreibung
Zusammenfassung:We present a new approach for developing a label-free biosensor for detection of DNA. The biosensor based on a biofunctionalized Double Tilt Fiber Bragg Grating transduces the presence of DNA into a change of visibility of fringes of its interference spectrum. Real-time spectral measurement results are reported, showing that a 10nM DNA solution induces a 10% modulation of the corresponding fringes visibility.
DOI:10.1109/IWBP.2011.5954849