Simulating Biological Pathways with a Continuous Petri Net Using Runge-Kutta Methods

Simulating Biological Pathways with a Continuous Petri Net Using Runge-Kutta Methods

The application of Petri nets to analyze and simulate biological pathways has been developed vigorously. Some of the modifications of Petri nets appeared to perform quantitative analysis of biological pathways: hybrid Petri net, timed Petri net, stochastic Petri net and so on. For a quantitative ana...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Sunku Kang, Byungwoo Lee, Jihoon Yang, Seonho Kim, Saejoon Kim
Format: Tagungsbericht
Sprache:eng
Schlagworte:
Analytical models
Biochemical analysis
Biological system modeling
Biology
Computational modeling
Computer simulation
Discrete event systems
Information technology
Petri nets
Stochastic processes
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The application of Petri nets to analyze and simulate biological pathways has been developed vigorously. Some of the modifications of Petri nets appeared to perform quantitative analysis of biological pathways: hybrid Petri net, timed Petri net, stochastic Petri net and so on. For a quantitative analysis of biological pathways, we propose to adopt Runge-Kutta methods to act on a continuous Petri net. We show that Runge-Kutta methods are applicable to a continuous Petri net in glycolysis and apoptosis pathways with reliable and efficient simulation results.
DOI:10.1109/FBIT.2007.62