Quantitative small animal fluorescence tomography using an ultra-fast gated image intensifier
Optical approaches to small animal in vivo molecular imaging provide high sensitivity, stable non-radioactive probes, and an extensive array of functional reporting strategies. However, quantitative whole body assays remain illusive. The quantitative accuracy of optical imaging is affected by the de...
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| creator | Patwardhan, S.V. Bloch, S. Achilefu, S. Culver, J.P. |
| description | Optical approaches to small animal in vivo molecular imaging provide high sensitivity, stable non-radioactive probes, and an extensive array of functional reporting strategies. However, quantitative whole body assays remain illusive. The quantitative accuracy of optical imaging is affected by the depth of the buried target and the heterogeneity of tissue optical properties. Tomography approaches, to obtaining in-vivo optical property maps, and whole body distributions of fluorescing probes, provide a strategy for improving the quality and quantitative accuracy of small animal optical imaging. Here we present a time-resolved, charged coupled device (CCD) based system for quantitative small animal fluorescence tomography |
| doi_str_mv | 10.1109/IEMBS.2006.259942 |
| format | Conference Proceeding |
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Here we present a time-resolved, charged coupled device (CCD) based system for quantitative small animal fluorescence tomography</description><subject>Animals</subject><subject>Fluorescence</subject><subject>Image intensifiers</subject><subject>In vivo</subject><subject>Molecular imaging</subject><subject>Optical arrays</subject><subject>Optical imaging</subject><subject>Optical sensors</subject><subject>Probes</subject><subject>Tomography</subject><issn>1557-170X</issn><isbn>9781424400324</isbn><isbn>1424400325</isbn><fulltext>true</fulltext><rsrctype>conference_proceeding</rsrctype><creationdate>2006</creationdate><recordtype>conference_proceeding</recordtype><sourceid>6IE</sourceid><sourceid>RIE</sourceid><recordid>eNotTs1KAzEYDKjYUvsA4iUvsDXJl91sjlqqFioi9uBFyrfplzWy3ZZNVvDtDehcZmB-GMaupVhIKeztevV8_7ZQQlQLVVqr1RmbW1NLrbQWApQ-Z1NZlqaQRrxP2DzGL5EBNtvqkk2ksbqSIKbs43XEPoWEKXwTjwfsOo59yMx9Nx4Hio56RzwdD8d2wNPnDx9j6Nsc4mOXBiw8xsRbTLTnudYSD32iPgYfaLhiFx67SPN_nrHtw2q7fCo2L4_r5d2mCFakAjwIkLRvlKs8SqgbqvfkS2GUEc5ZrIwxDSpnvaldBUDZyboBMIocwozd_M0GItqdhvxj-NlpXSnQBn4B4XRX4g</recordid><startdate>200608</startdate><enddate>200608</enddate><creator>Patwardhan, S.V.</creator><creator>Bloch, S.</creator><creator>Achilefu, S.</creator><creator>Culver, J.P.</creator><general>IEEE</general><scope>6IE</scope><scope>6IH</scope><scope>CBEJK</scope><scope>RIE</scope><scope>RIO</scope></search><sort><creationdate>200608</creationdate><title>Quantitative small animal fluorescence tomography using an ultra-fast gated image intensifier</title><author>Patwardhan, S.V. ; Bloch, S. ; Achilefu, S. ; Culver, J.P.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-i90t-3f3031edb2c6fa138be8def507270cc9a6777ba2c9f78c633e0729f7b3372eca3</frbrgroupid><rsrctype>conference_proceedings</rsrctype><prefilter>conference_proceedings</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Animals</topic><topic>Fluorescence</topic><topic>Image intensifiers</topic><topic>In vivo</topic><topic>Molecular imaging</topic><topic>Optical arrays</topic><topic>Optical imaging</topic><topic>Optical sensors</topic><topic>Probes</topic><topic>Tomography</topic><toplevel>online_resources</toplevel><creatorcontrib>Patwardhan, S.V.</creatorcontrib><creatorcontrib>Bloch, S.</creatorcontrib><creatorcontrib>Achilefu, S.</creatorcontrib><creatorcontrib>Culver, J.P.</creatorcontrib><collection>IEEE Electronic Library (IEL) Conference Proceedings</collection><collection>IEEE Proceedings Order Plan (POP) 1998-present by volume</collection><collection>IEEE Xplore All Conference Proceedings</collection><collection>IEEE Electronic Library (IEL)</collection><collection>IEEE Proceedings Order Plans (POP) 1998-present</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Patwardhan, S.V.</au><au>Bloch, S.</au><au>Achilefu, S.</au><au>Culver, J.P.</au><format>book</format><genre>proceeding</genre><ristype>CONF</ristype><atitle>Quantitative small animal fluorescence tomography using an ultra-fast gated image intensifier</atitle><btitle>2006 International Conference of the IEEE Engineering in Medicine and Biology Society</btitle><stitle>IEMBS</stitle><date>2006-08</date><risdate>2006</risdate><spage>2675</spage><epage>2678</epage><pages>2675-2678</pages><issn>1557-170X</issn><isbn>9781424400324</isbn><isbn>1424400325</isbn><abstract>Optical approaches to small animal in vivo molecular imaging provide high sensitivity, stable non-radioactive probes, and an extensive array of functional reporting strategies. 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| subjects | Animals Fluorescence Image intensifiers In vivo Molecular imaging Optical arrays Optical imaging Optical sensors Probes Tomography |
| title | Quantitative small animal fluorescence tomography using an ultra-fast gated image intensifier |
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