Canonical piecewise-linear approximation of nonlinear cellular growth

In this paper we develop and improve some piecewise-linear approximations of nonlinear cellular growth using orthonormal canonical piecewise linear functions. The work is with the mammalian cells BHK (baby hamster kidney) in bioreactor in batch and continuous mode operation. Preliminary results base...

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Hauptverfasser:	Mojica, E., Gauthier, A., Rakoto-Ravalontsalama, N.
Format:	Tagungsbericht
Sprache:	eng
Schlagworte:	Biological system modeling Biological systems Bioreactor Bioreactors Mathematical model Nonlinear dynamical systems nonlinear dynamics Pediatrics Piecewise linear approximation Piecewise linear techniques piecewise-linear (PWL) models Sugar USA Councils
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Beschreibung
Zusammenfassung:	In this paper we develop and improve some piecewise-linear approximations of nonlinear cellular growth using orthonormal canonical piecewise linear functions. The work is with the mammalian cells BHK (baby hamster kidney) in bioreactor in batch and continuous mode operation. Preliminary results based on experimental validation show that this piecewise linear approximation is well suited for modeling such nonlinear dynamics.
ISSN:	0191-2216
DOI:	10.1109/CDC.2007.4434461