Dependence of Frequency and Magnetic field on Self Heating Effect of NiFe2O4 Nanoparticles for Hyperthermia

The aim of this investigation is to study the properties of superparamagnetic (SPM) ferrite nanoparticles with a specially designed RF-induced LC-circuit system for hyperthermia in both isolated solid state nanoparticle powders and cell culture media. The effect of nanoparticle quantity, as well as the magnetic field strength and operating frequency, on the maximum temperature rise for hyperthermia applications was studied. Besides the physical and magnetic properties of the nanoparticles, the physical origin of temperature rise and specific absorption rate will be considered to explore the possibility for real clinical treatments.