FEATURE-BASED VS. INTENSITY-BASED BRAIN IMAGE REGISTRATION: COMPREHENSIVE COMPARISON USING MUTUAL INFORMATION
We propose a mutual information-based method for quantitative evaluation of the deformable registration algorithms at three levels: global, voxel-wise and anatomical structure. We compare two fully deformable registration algorithms: feature-based HAMMER and a set of intensity-based algorithms (FEM-...
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| creator | Teverovskiy, L.A. Carmichael, O.T. Aizenstein, H.J. Lazar, N. Liu, Y. |
| description | We propose a mutual information-based method for quantitative evaluation of the deformable registration algorithms at three levels: global, voxel-wise and anatomical structure. We compare two fully deformable registration algorithms: feature-based HAMMER and a set of intensity-based algorithms (FEM-Demons) in the ITK package. Evaluation is carried out using the AAE template image with 116 labeled anatomical structures and a set of 59 MR brain images: 20 normal controls (CTE), 20 Alzheimer's disease patients (AD) and 19 mild cognitive impairment patients (MCI). We show that both HAMMER and FEM-Demons perform significantly better than an affine registration algorithm, FLIRT, at all three levels. At the global level, FEM-Demons outperforms HAMMER on the images of AD and MCI patients. At the local and anatomical levels, FEM-Demons and HAMMER dominate each other on different brain regions. |
| doi_str_mv | 10.1109/ISBI.2007.356917 |
| format | Conference Proceeding |
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We show that both HAMMER and FEM-Demons perform significantly better than an affine registration algorithm, FLIRT, at all three levels. At the global level, FEM-Demons outperforms HAMMER on the images of AD and MCI patients. 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| fulltext | fulltext_linktorsrc |
| identifier | ISSN: 1945-7928 |
| ispartof | 2007 4th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, 2007, p.576-579 |
| issn | 1945-7928 1945-8452 |
| language | eng |
| recordid | cdi_ieee_primary_4193351 |
| source | IEEE Electronic Library (IEL) Conference Proceedings |
| subjects | Anatomical structure Biomedical imaging Brain Deformable models Entropy Finite element methods Image registration Image segmentation Mutual information Packaging |
| title | FEATURE-BASED VS. INTENSITY-BASED BRAIN IMAGE REGISTRATION: COMPREHENSIVE COMPARISON USING MUTUAL INFORMATION |
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