Surface enhanced Raman spectra in biochemical molecules and cell detection

Surface enhanced Raman spectra in biochemical molecules and cell detection

This work presents the quantitative detection of creatinine molecules and SERS signal from a single cell. Through the utilization of gold nanoparticles, we can measure the lower concentration of specimens. In biochemical molecules analysis, quantification of creatinine in human urine sample is demon...

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Hauptverfasser: Tsuei-Lian Wang, Fang-Ying Peng, Hui-Hsin Lu, Yung-Ta Hung, Tung-Jing Fang, Huihua Kenny Chiang
Format: Tagungsbericht
Sprache:eng
Schlagworte:
Band pass filters
Biomedical optical imaging
Gold
Humans
Optical scattering
Optical surface waves
Raman scattering
Rough surfaces
Spectroscopy
Surface roughness
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Zusammenfassung:This work presents the quantitative detection of creatinine molecules and SERS signal from a single cell. Through the utilization of gold nanoparticles, we can measure the lower concentration of specimens. In biochemical molecules analysis, quantification of creatinine in human urine sample is demonstrated. The correlation coefficient can be reached as high as 0.99 for mixture sample, and 0.93 for human subject analysis.
DOI:10.1109/APBP.2004.1412276