Neuroendocrine tissue engineering in rotating wall vessel bioreactors under simulated microgravity conditions

Neuroendocrine tissue engineering in rotating wall vessel bioreactors under simulated microgravity conditions

The low-shear, microgravity-simulating cell culture environment in rotating wall vessel (RWV) bioreactors is well suited for generating differentiated 3-D tissue constructs (organoids). Biochemical, immunological and molecular biological techniques, including cDNA arrays, were used to analyze signal...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Lelkes, P.I., Akhtar, N., Lelkes, E., Maltz, L., Arthur, R., Wiederholt, J., Unsworth, B.R.
Format: Tagungsbericht
Sprache:eng
Schlagworte:
Biochemical analysis
Biological system modeling
Biological techniques
Bioreactors
Gene expression
Immune system
Parkinson's disease
Plugs
Signal analysis
Tissue engineering
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The low-shear, microgravity-simulating cell culture environment in rotating wall vessel (RWV) bioreactors is well suited for generating differentiated 3-D tissue constructs (organoids). Biochemical, immunological and molecular biological techniques, including cDNA arrays, were used to analyze signal transduction, catecholamine contents, and gene expression in 3-D tissue-like constructs of PC12 pheochromocytoma cells grown for
ISSN:1094-687X
1558-4615
DOI:10.1109/IEMBS.2001.1017422