Are Peripheral Blood Derived Inflammation Markers Prognostic Indicators in Breast Cancer?

Objective: Peripheral blood derived inflammation based scores are proposed as prognostic markers in solid tumors especially in gastrointestinal system. We aimed to investigate the association between neutrophyl/lymphocyte ratio (NLR, platelet/lymphocyte ratio (PLR) and breast cancer in means of prognostic fo recast. Methods: Of 190 patients diagnosed and operated for breast cancer. 160 patients with available pretreatment blood count were included. Ultrasound, mammography, and pathology results were also recorded. Results: The median age was 50 years at the time of diagnosis (28-90 years). Family history was positive in 11 patients. There were 139 patients with invasive ductal carcinoma, 15 patients with invasive lobuler carcinoma. There was no association with histopathological type of the tumor and peripheral blood derived inflammation markers. The difference in PLR between T1 and T4 tumors was statistically significant. Also both NLR and PLR were significant when N0 patients compared with N1 patients (p