Effectiveness of different pharmacological approaches on post-ovariohysterectomy urinary incontinence in the bitch

In this study, the effectiveness of different pharmacological approaches on urinary incontinence encountered following ovariohysterectomy in the bitch was investigated. Eleven ovariohysterectomised bitches were used. Ephedrine hydrochloride (EHCl) tablets were used at the dose of 2 mg/kg twice a day in group I (n = 6). EHCl treatment was followed by Estradiol Benzoate administrations in cases, which did not recover totally. Estriol (Incurin®) was used (1 mg/kg/dog PO) for first seven days and a half dose was used for consecutive days in group II (n = 5). Clinical signs diminished in 50% of EHCl treated bitches and a total recovery was observed in 33.3% of cases. Total recovery rate was 66.7% after Estradiol Benzoate treatment. Duration of the treatments in group I was between 10 - 16 days. Incurin® (Estriol) treatment was effective in 80% of cases and duration of treatments including half dose administrations was 9 - 14 days. While additional treatment was needed in some of EHCl treated dogs, no recurrences were observed in group II. In conclusion, Estriol treatment is highly effective in postovariohysterectomy urinary incontinence in the bitch.