Prognostic Factors Affecting Survival In Patients With Operable Non-Small Cell Lung Cancer: Single Center Experience and Review of The Literature

Objective: Although early-stage lung cancer patients are curable, the prognosis is limited and the 5-year survival rates range from 40 to 65 percent. In this study, clinicopathologic features, treatment responses and prognostic factors of non-small cell lung cancer patients treated with surgery were investigated. Methods: Seven-hundred-thirty-eight non-small cell lung cancer patients diagnosed and followed up between the years of 1999 and 2009 were evaluated retrospectively. Eighty patients who underwent surgery were included in the study. Results: There were 71 male and 9 female patients with the median age of 55 years (range, 39 to 71). Forty-six-point-three percent of the patients had squmous cell cancer and 35 % had adenocarcinoma. Thirty-one patients had stage I, 30 had stage II and 19 had stage IIIA disease. Forty-six percent of the patients had adjuvant radiotherapy and 50.7% had adjuvant chemotherapy. The median follow-up time after diagnosis was 34.2 months (range, 12 -132), t