Isolated V-Lesion in an ABO-Incompatible Kidney Transplant Recipient Receiving Rituximab

We report an ABO-incompatible kidney transplant performed on a 69-year-old female patient, whose donor was her 69-year-old husband. The patient received an immunosuppressive protocol using rituximab without splenectomy. Renal biopsy was done on posttransplant day 8 due to poor early graft function,...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Experimental and clinical transplantation 2019-10, Vol.17 (5), p.678-680
Hauptverfasser: Iwai, Tomoaki, Uchida, Junji, Kabei, Kazuya, Nishide, Shunji, Kuwabara, Nobuyuki, Naganuma, Toshihide, Kumada, Norihiko, Takemoto, Yoshiaki, Nakatani, Tatsuya
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:We report an ABO-incompatible kidney transplant performed on a 69-year-old female patient, whose donor was her 69-year-old husband. The patient received an immunosuppressive protocol using rituximab without splenectomy. Renal biopsy was done on posttransplant day 8 due to poor early graft function, and an isolated v-lesion was found, which responded to steroid pulse therapy and gusperimus hydrochloride administration. Our results indicate that isolated v-lesions can occur in ABO-incompatible kidney transplant recipients receiving rituximab and that this finding should be treated as acute rejection. To our knowledge, this is the first report of an isolated v-lesion in an ABO-incompatible kidney transplant recipient who had been administered rituximab.
ISSN:1304-0855
2146-8427
DOI:10.6002/ect.2017.0062