The Interaction Between Pathogens and the Host Coagulation System

Hongmin Sun Life Sciences Institute, University of Michigan, Ann Arbor, Michigan hongmin{at}umich.edu There is mounting evidence that the hemostatic system is critical in host responses to bacterial infection. Invasive bacteria have evolved virulence strategies to interact with host hemostatic facto...

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Veröffentlicht in:	Physiology (Bethesda, Md.) Md.), 2006-08, Vol.21 (4), p.281-288
1. Verfasser:	Sun, Hongmin
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bacterial Infections - physiopathology Blood Coagulation - genetics Blood Coagulation - physiology Blood-Borne Pathogens Fibrinogen - physiology Genetic Variation Hemostasis - physiology Humans Plasminogen - physiology Thrombosis - physiopathology
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Zusammenfassung:	Hongmin Sun Life Sciences Institute, University of Michigan, Ann Arbor, Michigan hongmin{at}umich.edu There is mounting evidence that the hemostatic system is critical in host responses to bacterial infection. Invasive bacteria have evolved virulence strategies to interact with host hemostatic factors such as plasminogen and fibrinogen for infection. Furthermore, genetic variations in host hemostatic factors also influence host response to bacterial infection.
ISSN:	1548-9213 1548-9221
DOI:	10.1152/physiol.00059.2005