Volumetric response of right ventricle during progressive supine exercise in men

P. Mols, C. H. Huynh, N. Naeije and H. R. Ham Department of Internal Medicine, Saint-Pierre University Hospital, Brussels, Belgium. Right ventricular (RV) adaptation to supine exercise has been studied in 10 young male volunteers by 81mKr electrocardiogram (ECG)-gated radionuclide ventriculography....

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Veröffentlicht in:American journal of physiology. Heart and circulatory physiology 1991-09, Vol.261 (3), p.H751-H754
Hauptverfasser: Mols, P, Huynh, C. H, Naeije, N, Ham, H. R
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Sprache:eng
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Zusammenfassung:P. Mols, C. H. Huynh, N. Naeije and H. R. Ham Department of Internal Medicine, Saint-Pierre University Hospital, Brussels, Belgium. Right ventricular (RV) adaptation to supine exercise has been studied in 10 young male volunteers by 81mKr electrocardiogram (ECG)-gated radionuclide ventriculography. During progressive supine exercise, the ejection fraction gradually increased from a mean value of 46% at rest up to 60% at a maximal exercise level. End-diastolic volume however remained unchanged at a low exercise level and even slightly decreased at a higher exercise level. Little or no change in end-diastolic volume and an increase in ejection fraction produced a significant decrease in end-systolic volume and a net increase in stroke volume. These results indicate that the Frank-Starling mechanism does not contribute to the increase in right ventricular stroke volume during progressive supine exercise, but the increase in right ventricular stroke volume rather seems related to an increased contractility, presumably mediated by an increased sympathetic activity.
ISSN:0363-6135
0002-9513
1522-1539
DOI:10.1152/ajpheart.1991.261.3.h751