Flexible Intensive Insulin Therapy in Adults With Type 1 Diabetes and High Risk for Severe Hypoglycemia and Diabetic Ketoacidosis

Flexible Intensive Insulin Therapy in Adults With Type 1 Diabetes and High Risk for Severe Hypoglycemia and Diabetic Ketoacidosis Response to Sämann et al. Mary E. Pennant , MMEDSCI , Mark D. Chatfield , MSC , W. Andy Coward , PHD and Les J.C. Bluck , PHD From the Medical Research Council Human Nutrition Research, Cambridge, U.K. Address correspondence to Mary Pennant, Medical Research Council Human Nutrition Research, Fulbourn Road, Cambridge, CB1 9NL, U.K. E-mail: mary.pennant{at}mrc-hnr.cam.ac.uk The recent subgroup analysis by Sämann et al. (1) examined the effectiveness of diabetes treatment and teaching programs (DTTPs) and advocated intensive insulin therapy combined with increased dietary freedom in individuals with type 1 diabetes who were at increased risk of hypoglycemia. There were significant reductions in hypoglycemic episodes, from 6.1 to 1.4 hypoglycemic events per patient per year, after participation. Sämann et al. concluded that DTTPs may reduce the occurrence of hypoglycemic episodes for those at risk, but, for several reasons, this … [Full Text of this Article]