Synthesis and Secretion of γ-Globulin by Lymph Node Cells

A microsomal system which incorporates 14 C-galactose into an endogeneous, specifically coprecipitable, γ-globulin acceptor is described and characterized. The product formed is compartmentalized within microsomes, and procedures for its solubilization are presented. Evidence indicating the selecti...

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Veröffentlicht in:The Journal of biological chemistry 1968-06, Vol.243 (12), p.3425
Hauptverfasser: Richard P. D'Amico, Milton Kern
Format: Artikel
Sprache:eng
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Zusammenfassung:A microsomal system which incorporates 14 C-galactose into an endogeneous, specifically coprecipitable, γ-globulin acceptor is described and characterized. The product formed is compartmentalized within microsomes, and procedures for its solubilization are presented. Evidence indicating the selective inhibition of incorporation into γ-globulin, without inhibition of incorporation into other protein acceptors, is also described.
ISSN:0021-9258
1083-351X