Glycans of bovine lactoferrin function as receptors for the type 1 fimbrial lectin of Escherichia coli

Glycans of bovine lactoferrin function as receptors for the type 1 fimbrial lectin of Escherichia coli

Bovine lactoferrin strongly inhibited the hemagglutination activity of type 1 fimbriated Escherichia coli. In addition, it agglutinated these bacteria. The agglutination reaction was specifically inhibited by glycopeptides derived from bovine lactoferrin or alpha-methyl-D-mannoside. These observatio...

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Veröffentlicht in:Infection and Immunity 1996-03, Vol.64 (3), p.1075-1077
Hauptverfasser: Teraguchi, S, Shin, K, Fukuwatari, Y, Shimamura, S
Format: Artikel
Sprache:eng
Schlagworte:
Agglutination
animal diseases
animal health
Animals
bacterial infections
Bacteriology
Biological and medical sciences
Cattle
Escherichia coli
Escherichia coli - metabolism
Fundamental and applied biological sciences. Psychology
Guinea Pigs
Hemagglutination
Lactoferrin - metabolism
Lectins - metabolism
Microbiology
Motility, taxis
Polysaccharides - metabolism
Receptors, Immunologic - metabolism
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Zusammenfassung:Bovine lactoferrin strongly inhibited the hemagglutination activity of type 1 fimbriated Escherichia coli. In addition, it agglutinated these bacteria. The agglutination reaction was specifically inhibited by glycopeptides derived from bovine lactoferrin or alpha-methyl-D-mannoside. These observations indicate that the glycans of bovine lactoferrin can serve as receptors for type 1 fimbrial lectin.
ISSN:0019-9567
1098-5522
DOI:10.1128/iai.64.3.1075-1077.1996