Caenorhabditis elegans as an Alternative Model Host for Legionella pneumophila, and Protective Effects of Bifidobacterium infantis

The survival times of Caenorhabditis elegans worms infected with Legionella pneumophila from day 7.5 or later after hatching were shorter than those of uninfected worms. However, nematodes fed bifidobacteria prior to Legionella infection were resistant to LEGIONELLA: These nematodes may act as a uni...

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Veröffentlicht in:	Applied and Environmental Microbiology 2010-06, Vol.76 (12), p.4105-4108
Hauptverfasser:	Komura, Tomomi, Yasui, Chikako, Miyamoto, Hiroshi, Nishikawa, Yoshikazu
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibiosis Bacteria Bifidobacterium - growth & development Bifidobacterium - metabolism Bifidobacterium - physiology Bifidobacterium infantis Biological and medical sciences Caenorhabditis elegans - microbiology Colony Count, Microbial Disease Models, Animal Drug resistance Fundamental and applied biological sciences. Psychology Hatching Legionella pneumophila - growth & development Legionella pneumophila - pathogenicity Microbiology Public Health Microbiology Survival Analysis Time Factors
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Zusammenfassung:	The survival times of Caenorhabditis elegans worms infected with Legionella pneumophila from day 7.5 or later after hatching were shorter than those of uninfected worms. However, nematodes fed bifidobacteria prior to Legionella infection were resistant to LEGIONELLA: These nematodes may act as a unique alternative host for Legionella research.
ISSN:	0099-2240 1098-5336 1098-6596
DOI:	10.1128/AEM.03021-09