Hidden Biomass of Intact Malaria Parasites in the Human Spleen

In this report, patients living in a malaria-endemic area underwent trauma-related splenectomy. In these asymptomatic patients who were naturally infected with Plasmodium falciparum or P. vivax, the predominant biomass of intact, infected red cells was in the spleen.

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Bibliographische Detailangaben
Veröffentlicht in:	The New England journal of medicine 2021-05, Vol.384 (21), p.2067-2069
Hauptverfasser:	Kho, Steven, Qotrunnada, Labibah, Leonardo, Leo, Andries, Benediktus, Wardani, Putu A.I, Fricot, Aurelie, Henry, Benoit, Hardy, David, Margyaningsih, Nur I, Apriyanti, Dwi, Puspitasari, Agatha M, Prayoga, Pak, Trianty, Leily, Kenangalem, Enny, Chretien, Fabrice, Safeukui, Innocent, del Portillo, Hernando A, Fernandez-Becerra, Carmen, Meibalan, Elamaran, Marti, Matthias, Price, Ric N, Woodberry, Tonia, Ndour, Papa A, Russell, Bruce M, Yeo, Tsin W, Minigo, Gabriela, Noviyanti, Rintis, Poespoprodjo, Jeanne R, Siregar, Nurjati C, Buffet, Pierre A, Anstey, Nicholas M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Animals Asexuality Asymptomatic Asymptomatic Infections Biomass Child Erythrocytes Erythrocytes - parasitology Female Humans Infections Life Sciences Malaria Malaria, Falciparum - parasitology Malaria, Vivax - parasitology Male Parasites Plasmodium falciparum - isolation & purification Plasmodium vivax - isolation & purification Spleen Spleen - parasitology Splenectomy Trauma Young Adult
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Beschreibung
Zusammenfassung:	In this report, patients living in a malaria-endemic area underwent trauma-related splenectomy. In these asymptomatic patients who were naturally infected with Plasmodium falciparum or P. vivax, the predominant biomass of intact, infected red cells was in the spleen.
ISSN:	0028-4793 1533-4406
DOI:	10.1056/NEJMc2023884