Zika Virus Outbreak on Yap Island, Federated States of Micronesia

Zika virus is a flavivirus known to cause human infection in Asia and Africa. This article describes an outbreak of Zika virus infection on Yap Island, Federated States of Micronesia, with predominant symptoms of rash, fever, arthralgia, and conjunctivitis. An estimated 73% of Yap residents 3 years of age or older became infected during the 4 months of the outbreak. This article describes an outbreak of Zika virus infection on Yap Island, Federated States of Micronesia, with predominant symptoms of rash, fever, arthralgia, and conjunctivitis. An estimated 73% of Yap residents 3 years of age or older became infected. Zika virus is a flavivirus (family Flaviviridae) related to West Nile, dengue, and yellow fever viruses. 1 Zika virus was isolated in 1947 from a rhesus monkey in the Zika forest near Entebbe, Uganda 2 ; its genome was sequenced in 2006. 3 There is serologic evidence of human Zika virus infection in Africa and Asia, and the virus has been isolated from humans in Uganda, Nigeria, and Senegal. 2 – 12 Zika virus is believed to be transmitted to humans by infected mosquitoes and has been isolated from Aedes africanus, Aedes luteocephalus, and Aedes aegypti . 13 – 16 No outbreaks and only 14 cases of . . .