Driving Role of Interleukin‐2–Related Regulatory CD4 + T Cell Deficiency in the Development of Lung Fibrosis and Vascular Remodeling in a Mouse Model of Systemic Sclerosis

Objective. Systemic sclerosis (SSc) is a debilitating autoimmune disease characterized by severe lung outcomes resulting in reduced life expectancy. Fra-2-transgenic mice offer the opportunity to decipher the relationships between the immune system and lung fibrosis. This study was undertaken to inv...

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Veröffentlicht in:	Arthritis & rheumatology (Hoboken, N.J.) N.J.), 2022-08, Vol.74 (8), p.1387-1398
Hauptverfasser:	Frantz, Camelia, Cauvet, Anne, Durand, Aurélie, Gonzalez, Virginie, Pierre, Rémi, Do Cruzeiro, Marcio, Bailly, Karine, Andrieu, Muriel, Orvain, Cindy, Avouac, Jérôme, Ottaviani, Mina, Thuillet, Raphaël, Tu, Ly, Guignabert, Christophe, Lucas, Bruno, Auffray, Cédric, Allanore, Yannick
Format:	Artikel
Sprache:	eng
Schlagworte:	Cardiology and cardiovascular system Ecology, environment Environmental Sciences Health Human health and pathology Life Sciences Pulmonology and respiratory tract Tissues and Organs
Online-Zugang:	Volltext
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