Bariatric surgery short-term outcomes in patients with obstructive sleep apnoea: the Severe Obesity Outcome Network prospective cohort

Background/objectives Although the benefits of bariatric surgery have been clearly established, it is not known whether they are as important in patients with obstructive sleep apnoea (OSA). Primary aim: to evaluate whether patients with moderate-to-severe OSA (apnoea-hypopnea index (AHI) ≥ 15 event...

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Veröffentlicht in:International Journal of Obesity 2021-11, Vol.45 (11), p.2388-2395
Hauptverfasser: Guggino, Jessica, Tamisier, Renaud, Betry, Cécile, Coumes, Sandrine, Arvieux, Catherine, Wion, Nelly, Reche, Fabian, Pépin, Jean-Louis, Borel, Anne-Laure
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Sprache:eng
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Zusammenfassung:Background/objectives Although the benefits of bariatric surgery have been clearly established, it is not known whether they are as important in patients with obstructive sleep apnoea (OSA). Primary aim: to evaluate whether patients with moderate-to-severe OSA (apnoea-hypopnea index (AHI) ≥ 15 events/h) treated by continuous positive airway pressure/non-invasive ventilation (median [IQR] adherence 6.5 h/night [5; 7.9] at baseline) lose the same amount of body weight 1 year after bariatric surgery as patients with no or mild OSA. Secondary objectives: to compare the evolution of type 2 diabetes and hypertension after bariatric surgery, and surgical complication rates between groups. Methods/subjects Analyses were performed in 371 patients included in a prospective cohort of bariatric surgery, the Severe Obesity Outcome Network cohort. Subjects having moderate-to-severe OSA ( n  = 210) at baseline were compared with other subjects ( n  = 161). Results Excess weight loss (%EWL) at 1 year was lower in patients with moderate-to-severe OSA than in patients without (64.9%EWL [46.9; 79.5] vs. 73.8%EWL [56.6; 89.3], p  
ISSN:0307-0565
1476-5497
0307-0565
DOI:10.1038/s41366-021-00903-5