Tenofovir DF/emtricitabine and efavirenz combination therapy for HIV infection in patients treated for tuberculosis: the ANRS 129 BKVIR trial

HIV-infected patients with TB need simplified, effective and well-tolerated antiretroviral regimens. The French ANRS 129 BKVIR open trial evaluated the once-daily tenofovir DF/emtricitabine and efavirenz combination, started within 12 weeks after TB treatment initiation, in antiretroviral-naive HIV-...

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Veröffentlicht in:Journal of antimicrobial chemotherapy 2016-03, Vol.71 (3), p.783-793
Hauptverfasser: Lortholary, Olivier, Roussillon, Caroline, Boucherie, Céline, Padoin, Christophe, Chaix, Marie-Laure, Breton, Guillaume, Rami, Agathe, Veziris, Nicolas, Patey, Olivier, Caumes, Eric, May, Thierry, Molina, Jean-Michel, Robert, Jérome, Tod, Michel, Fagard, Catherine, Chêne, Geneviève
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Sprache:eng
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Zusammenfassung:HIV-infected patients with TB need simplified, effective and well-tolerated antiretroviral regimens. The French ANRS 129 BKVIR open trial evaluated the once-daily tenofovir DF/emtricitabine and efavirenz combination, started within 12 weeks after TB treatment initiation, in antiretroviral-naive HIV-1-infected patients. Success was defined as an HIV-1 RNA
ISSN:0305-7453
1460-2091
DOI:10.1093/jac/dkv384