Does changing antiretroviral therapy in the first trimester for pregnancy-related concerns have an impact on viral suppression ?: Changing ART in pregnancy and viral suppression ?

OBJECTIVE:To determine whether changing antiretroviral therapy (ART) during pregnancy because of concern about fetal risks led to poorer virological outcomes.METHODS:All pregnancies in women with HIV-1 infection enrolled in the national multicenter prospective French Perinatal cohort at 14 week gest...

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Veröffentlicht in:Journal of acquired immune deficiency syndromes (1999) 2019-04, Vol.80 (5), p.574-584
Hauptverfasser: Peyronnet, Violaine, Warszawski, Josiane, Sibiude, Jeanne, Dialla, Olivia, Moine, Agnès Bourgeois, Bui, Eida, Toulza, Caroline Simon, Peretti, Delphine, Brunet-Cartier, Cécile, Avettand-Fenoël, Véronique, Le Chenadec, Jerome, Faye, Albert, Tubiana, Roland, Mandelbrot, Laurent
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Sprache:eng
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Zusammenfassung:OBJECTIVE:To determine whether changing antiretroviral therapy (ART) during pregnancy because of concern about fetal risks led to poorer virological outcomes.METHODS:All pregnancies in women with HIV-1 infection enrolled in the national multicenter prospective French Perinatal cohort at 14 week gestation or more were included between January 2005 and December 2015, if the mother was on ART at conception with a plasma viral load
ISSN:1525-4135
1944-7884
DOI:10.1097/QAI.0000000000001954