Generating anatomical models of the heart and the aorta from medical images for personalized physiological simulations

The anatomy and motion of the heart and the aorta are essential for patient-specific simulations of cardiac electrophysiology, wall mechanics and hemodynamics. Within the European integrated project euHeart, algorithms have been developed that allow to efficiently generate patient-specific anatomica...

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Veröffentlicht in:Medical & biological engineering & computing 2013-11, Vol.51 (11), p.1209-1219
Hauptverfasser: Weese, J., Groth, A., Nickisch, H., Barschdorf, H., Weber, F. M., Velut, J., Castro, M., Toumoulin, C., Coatrieux, J. L., De Craene, M., Piella, G., Tobón-Gomez, C., Frangi, A. F., Barber, D. C., Valverde, I., Shi, Y., Staicu, C., Brown, A., Beerbaum, P., Hose, D. R.
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container_end_page 1219
container_issue 11
container_start_page 1209
container_title Medical & biological engineering & computing
container_volume 51
creator Weese, J.
Groth, A.
Nickisch, H.
Barschdorf, H.
Weber, F. M.
Velut, J.
Castro, M.
Toumoulin, C.
Coatrieux, J. L.
De Craene, M.
Piella, G.
Tobón-Gomez, C.
Frangi, A. F.
Barber, D. C.
Valverde, I.
Shi, Y.
Staicu, C.
Brown, A.
Beerbaum, P.
Hose, D. R.
description The anatomy and motion of the heart and the aorta are essential for patient-specific simulations of cardiac electrophysiology, wall mechanics and hemodynamics. Within the European integrated project euHeart, algorithms have been developed that allow to efficiently generate patient-specific anatomical models from medical images from multiple imaging modalities. These models, for instance, account for myocardial deformation, cardiac wall motion, and patient-specific tissue information like myocardial scar location. Furthermore, integration of algorithms for anatomy extraction and physiological simulations has been brought forward. Physiological simulations are linked closer to anatomical models by encoding tissue properties, like the muscle fibers, into segmentation meshes. Biophysical constraints are also utilized in combination with image analysis to assess tissue properties. Both examples show directions of how physiological simulations could provide new challenges and stimuli for image analysis research in the future.
doi_str_mv 10.1007/s11517-012-1027-0
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subjects Algorithms
Aorta - anatomy & histology
Aorta - physiology
Bioengineering
Biomedical and Life Sciences
Biomedical engineering
Biomedical Engineering and Bioengineering
Biomedicine
Cardiology
Computer Applications
Computer based modeling
Computer Science
Computer Simulation
Coronary Angiography
Coronary vessels
Deformation
Electrophysiologic Techniques, Cardiac
Engineering Sciences
Heart
Heart - anatomy & histology
Heart - physiology
Hemodynamics
Human Physiology
Humans
Imaging
Imaging, Three-Dimensional
Life Sciences
Magnetic Resonance Angiography
Medical imaging
Modeling and Simulation
Models, Cardiovascular
Patients
Physiology
Precision Medicine
Propagation
Radiology
Signal and Image processing
Simulation
Special Issue - Review
Studies
title Generating anatomical models of the heart and the aorta from medical images for personalized physiological simulations
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