Pathological lesions in colonic biopsies during Parkinson’s disease

[...]demonstrating (1) the ability to study the ENS using routine colonic biopsies and (2) the presence of lesions characteristics of PD could be relevant for an early diagnosis of the disease and to better understand its pathophysiology.

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Bibliographische Detailangaben
Veröffentlicht in:	Gut 2008-12, Vol.57 (12), p.1741-1743
Hauptverfasser:	Lebouvier, T, Chaumette, T, Damier, P, Coron, E, Touchefeu, Y, Vrignaud, S, Naveilhan, P, Galmiche, J-P, Bruley des Varannes, S, Derkinderen, P, Neunlist, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged alpha-Synuclein - analysis Biopsy Case-Control Studies Colon - innervation Colon - pathology Constipation Constipation - pathology Dopamine Enteric Nervous System - pathology Human health and pathology Humans Hépatology and Gastroenterology Immunohistochemistry Life Sciences Male Medical screening Nerve Degeneration - pathology Neurons and Cognition Parkinson Disease - pathology Parkinson's disease Pilot Projects Submucous Plexus - pathology
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Beschreibung
Zusammenfassung:	[...]demonstrating (1) the ability to study the ENS using routine colonic biopsies and (2) the presence of lesions characteristics of PD could be relevant for an early diagnosis of the disease and to better understand its pathophysiology.
ISSN:	0017-5749 1468-3288
DOI:	10.1136/gut.2008.162503