Anti-androgenic activities of environmental pesticides in the MDA-kb2 reporter cell line

Pesticides have been suspected to act as endocrine disruptive compounds (EDCs) through several mechanisms of action, however data are still needed for a number of currently used pesticides. In the present study, 30 environmental pesticides selected from different chemical classes (azole, carbamate,...

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Veröffentlicht in:	Toxicology in vitro 2010-10, Vol.24 (7), p.1979-1985
Hauptverfasser:	Aït-Aïssa, S., Laskowski, S., Laville, N., Porcher, J.-M., Brion, F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Androgen receptor Androgen Receptor Antagonists - administration & dosage Androgen Receptor Antagonists - toxicity Androgen receptors Anti-androgenic potency Cell Line, Tumor Dihydrotestosterone - toxicity Endocrine Disruptors - administration & dosage Endocrine Disruptors - toxicity Genes, Reporter - drug effects Glucocorticoid receptor Humans Inhibitory Concentration 50 Life Sciences Pesticides Pesticides - toxicity Reporter gene assay Time Factors Toxicology Transcription, Genetic - drug effects
Online-Zugang:	Volltext
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