Home health monitoring and personal lifestyle assistants to improve nutritional habits in adults: The Cook to Health trial, C2H

Unhealthy lifestyles are major factors contributing to chronic conditions. By proposing suitable menu designs and easy recipes, Open Food Service internet app with connected food processors will bring easy solutions to cook and progressively develop healthy dietary habits at home. A randomized controlled trial will test in healthy subjects the ability of connected food processors to modify dietary habits and to improve metabolic homeostasis, assessed with a systems health monitoring, all at home. This is a prospective, randomized, single blind and 12 month controlled trial in Grenoble and Aberystwyth. Double consent using Zelen method of randomization is used. Healthy volunteers, 25–50 years old, living in a family, be the main person who prepares meals and be able to use the personal health monitoring devices are recruited, 100 in Grenoble and 60 in Aberystwyth. The principal objective is to evaluate the ability of connected cook devices to modify dietary habits measured by a clinically significant increase of 1 quintile in Alternate Healthy Eating Index-2010. Secondary objectives are a) to demonstrate feasibility to collect data and specimen at home over one year; b) to compare changes at one year in quality of life, body composition, physical activities, sleep duration, gut microbiote; c) to describe urinary metabolomics patterns that are able to report recent dietary habits. Elementary descriptive analysis and integration of all data sets vertically and longitudinally and comparisons between groups will be carried out. The two two studies are conducted separately and analysed in meta-analysis. Les modes de vie Occidentaux sont des facteurs majeurs contribuant aux développement des maladies chroniques. En proposant des menus adaptés et des recettes faciles à réaliser, l’application internet Open Food Service et ses outils de cuisine connectés proposent des solutions faciles pour cuisiner et développer progressivement des habitudes alimentaires plus saines à domicile. Un essai contrôlé randomisé testera chez des sujets sains la capacité des outils de cuisine connectés à modifier les habitudes alimentaires et à améliorer l’homéostasie métabolique des volontaires. Par ailleurs, l’ensemble de l’évaluation clinique se fera à domicile. Il s’agit d’un essai, randomisé, en simple aveugle et contrôlé sur 12 mois à Grenoble (n=100), France et Aberystwyth (n=60), Pays de Galles. Le double consentement est utilisé avec la méthode de randomisation de Zelen. Des femm