Usefulness of sudomotor function assessment in individuals with type-2 diabetes: A case–control study

AbstractBackground Early screening for type 2 diabètes is crucial to prevent complications such as peripheral neuropathy and their detrimental effects on quality of life and morbidity. Sudomotor function assessment may play a pivotai rôle in this regard.Objective The aim of this study was to evaluate the usefulness of sudomotor function assessment, derived from electrochemi- cal skin conductance (ESC) measurement, for the diagnosis of diabètes in patients.Methods This case-control study was conducted at the University Hospital of Lomé in Togo and included 304 people with Diabètes and 475 control subjects. Sudomotor function was assessed in both groups using a single de vice (Sudoscan2, version SU2 01266). The ESC of the left and right hands and feet were measured in each subject and then averaged. A comprehensive examination was performed, and démographie, anthropométrie, and clinical data were collected. Consent was obtained from ail participants.Results The study found that people with Diabètes were significantly older, had a higher body mass index (BMI), and were more frequently male than the control group (médian and [interquartile]: 57 [48-65] vs. 41 [30-52] years, p