The effect of flushing of the common bile duct on hepatobiliary markers and short‐term outcomes in dogs undergoing cholecystectomy for the management of gall bladder mucocele: A randomized controlled prospective study

Objective To determine the effect of flushing of the common bile duct (CBD) on hepatobiliary markers and short‐term outcome in dogs undergoing cholecystectomy for the management of gallbladder mucocele (GBM). Study design Randomized, controlled, prospective study. Animals Thirty‐two client‐owned dogs. Methods Dogs were allocated randomly to either a “flush” group or a “non‐flush group.” Flushing was performed in a normograde fashion, followed by a routine cholecystectomy. Data collected included presenting clinical signs, preoperative and 3‐day postoperative hepatobiliary markers (alkaline phosphatase, ALP; alanine aminotransferase, ALT; gamma glumatyl‐transferase, GGT; bilirubin; cholesterol; triglycerides), duration of hospitalization, and complications. These data were compared between groups. Results Sixteen dogs were enrolled in each group. One dog (in the flush group) was excluded following diagnosis of hepatic lymphoma. Border terriers were overrepresented (20/31). Overall, there were marked reductions from preoperative to 3 days postoperative in serum bilirubin (p = .004), ALP (p = .020), ALT (p