Two alleles for rhesus macaque GPR15 (BOB)
CHEMOKINE RECEPTORS are used for fusion by primate immunodeficiency viruses. CXCR4 and CCR5 are the two main coreceptors for HIV: they are used by lymphotropic and macrophage-tropic strains of viruses, respectively. Many other chemokine receptors have been described to be involved in fusion, at leas...
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| Veröffentlicht in: | AIDS research and human retroviruses 1999-07, Vol.15 (10), p.945-947 |
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| container_title | AIDS research and human retroviruses |
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| creator | PRETET, J.-L BRUSSEL, A GUILLET, J.-G BUTOR, C |
| description | CHEMOKINE RECEPTORS are used for fusion by primate immunodeficiency viruses. CXCR4 and CCR5 are the two main coreceptors for HIV: they are used by lymphotropic and macrophage-tropic strains of viruses, respectively. Many other chemokine receptors have been described to be involved in fusion, at least in vitro. One of these, GPR15 (also known as BOB), is particularly efficient for fusion of SIV strains. We show the existence of two alleles for gpr15 in rhesus macaques. The two alleles are well represented in our colony, as two randomly selected animals were heterozygotes. The existence of two or more alleles has been described for other chemokine receptors. |
| doi_str_mv | 10.1089/088922299310665 |
| format | Article |
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CXCR4 and CCR5 are the two main coreceptors for HIV: they are used by lymphotropic and macrophage-tropic strains of viruses, respectively. Many other chemokine receptors have been described to be involved in fusion, at least in vitro. One of these, GPR15 (also known as BOB), is particularly efficient for fusion of SIV strains. We show the existence of two alleles for gpr15 in rhesus macaques. The two alleles are well represented in our colony, as two randomly selected animals were heterozygotes. The existence of two or more alleles has been described for other chemokine receptors.</description><identifier>ISSN: 0889-2229</identifier><identifier>EISSN: 1931-8405</identifier><identifier>DOI: 10.1089/088922299310665</identifier><identifier>PMID: 10408732</identifier><identifier>CODEN: ARHRE7</identifier><language>eng</language><publisher>Larchmont, NY: Liebert</publisher><subject>AIDS/HIV ; Alleles ; Amino Acid Sequence ; Animals ; Bacterial Proteins - genetics ; Base Sequence ; Biological and medical sciences ; DNA, Complementary ; Experimental viral diseases and models ; Fundamental and applied biological sciences. Psychology ; Genes. 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CXCR4 and CCR5 are the two main coreceptors for HIV: they are used by lymphotropic and macrophage-tropic strains of viruses, respectively. Many other chemokine receptors have been described to be involved in fusion, at least in vitro. One of these, GPR15 (also known as BOB), is particularly efficient for fusion of SIV strains. We show the existence of two alleles for gpr15 in rhesus macaques. The two alleles are well represented in our colony, as two randomly selected animals were heterozygotes. The existence of two or more alleles has been described for other chemokine receptors.</description><subject>AIDS/HIV</subject><subject>Alleles</subject><subject>Amino Acid Sequence</subject><subject>Animals</subject><subject>Bacterial Proteins - genetics</subject><subject>Base Sequence</subject><subject>Biological and medical sciences</subject><subject>DNA, Complementary</subject><subject>Experimental viral diseases and models</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Genes. Genome</subject><subject>Human immunodeficiency virus</subject><subject>Humans</subject><subject>Infectious diseases</subject><subject>Life Sciences</subject><subject>Macaca mulatta</subject><subject>Macaca rhesus</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Molecular and cellular biology</subject><subject>Molecular genetics</subject><subject>Molecular Sequence Data</subject><subject>Sigma Factor</subject><subject>Simian immunodeficiency virus</subject><subject>Transcription Factors</subject><subject>Viral diseases</subject><issn>0889-2229</issn><issn>1931-8405</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1999</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqF0MFLwzAUBvAgipvTszfpQcQJdS9Jk7wct6FOGExknkuapqzSrbNZFf97WzpUvHhKyPvl4_ERck7hlgLqESBqxpjWnIKU4oD0aXMNMQJxSPrtNGzHPXLi_SsANFgckx6FCFBx1ic3y48yMEXhCueDrKyCauV87YO1seatdsHD0zMVwfVkMRmekqPMFN6d7c8Bebm_W05n4Xzx8Dgdz0PLUe1CGwmUmUizRFHDrUqjlBpIXcatQxCWCdCQoUTlEkROubUysS7VQnJEw_iADLvclSnibZWvTfUZlyaPZ-N53L5BJIGBVO-0sVed3VZls67fxevcW1cUZuPK2sdSo6ZKsH8hVUxKJtrEUQdtVXpfuex7BQpx23n8p_Pmx8U-uk7WLv3lu5IbcLkHxltTZJXZ2Nz_OERFOfAvWHSECg</recordid><startdate>19990701</startdate><enddate>19990701</enddate><creator>PRETET, J.-L</creator><creator>BRUSSEL, A</creator><creator>GUILLET, J.-G</creator><creator>BUTOR, C</creator><general>Liebert</general><general>Mary Ann Liebert</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7U9</scope><scope>H94</scope><scope>7X8</scope><scope>1XC</scope></search><sort><creationdate>19990701</creationdate><title>Two alleles for rhesus macaque GPR15 (BOB)</title><author>PRETET, J.-L ; BRUSSEL, A ; GUILLET, J.-G ; BUTOR, C</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c387t-c4586f5dfb71a3c7d4d1a0def3ce805c25090f8687eb88313cc6bced956388a23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1999</creationdate><topic>AIDS/HIV</topic><topic>Alleles</topic><topic>Amino Acid Sequence</topic><topic>Animals</topic><topic>Bacterial Proteins - genetics</topic><topic>Base Sequence</topic><topic>Biological and medical sciences</topic><topic>DNA, Complementary</topic><topic>Experimental viral diseases and models</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Genes. Genome</topic><topic>Human immunodeficiency virus</topic><topic>Humans</topic><topic>Infectious diseases</topic><topic>Life Sciences</topic><topic>Macaca mulatta</topic><topic>Macaca rhesus</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Molecular and cellular biology</topic><topic>Molecular genetics</topic><topic>Molecular Sequence Data</topic><topic>Sigma Factor</topic><topic>Simian immunodeficiency virus</topic><topic>Transcription Factors</topic><topic>Viral diseases</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>PRETET, J.-L</creatorcontrib><creatorcontrib>BRUSSEL, A</creatorcontrib><creatorcontrib>GUILLET, J.-G</creatorcontrib><creatorcontrib>BUTOR, C</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>MEDLINE - Academic</collection><collection>Hyper Article en Ligne (HAL)</collection><jtitle>AIDS research and human retroviruses</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>PRETET, J.-L</au><au>BRUSSEL, A</au><au>GUILLET, J.-G</au><au>BUTOR, C</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Two alleles for rhesus macaque GPR15 (BOB)</atitle><jtitle>AIDS research and human retroviruses</jtitle><addtitle>AIDS Res Hum Retroviruses</addtitle><date>1999-07-01</date><risdate>1999</risdate><volume>15</volume><issue>10</issue><spage>945</spage><epage>947</epage><pages>945-947</pages><issn>0889-2229</issn><eissn>1931-8405</eissn><coden>ARHRE7</coden><abstract>CHEMOKINE RECEPTORS are used for fusion by primate immunodeficiency viruses. CXCR4 and CCR5 are the two main coreceptors for HIV: they are used by lymphotropic and macrophage-tropic strains of viruses, respectively. Many other chemokine receptors have been described to be involved in fusion, at least in vitro. One of these, GPR15 (also known as BOB), is particularly efficient for fusion of SIV strains. We show the existence of two alleles for gpr15 in rhesus macaques. The two alleles are well represented in our colony, as two randomly selected animals were heterozygotes. The existence of two or more alleles has been described for other chemokine receptors.</abstract><cop>Larchmont, NY</cop><pub>Liebert</pub><pmid>10408732</pmid><doi>10.1089/088922299310665</doi><tpages>3</tpages></addata></record> |
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| source | Mary Ann Liebert Online Subscription; MEDLINE; Alma/SFX Local Collection |
| subjects | AIDS/HIV Alleles Amino Acid Sequence Animals Bacterial Proteins - genetics Base Sequence Biological and medical sciences DNA, Complementary Experimental viral diseases and models Fundamental and applied biological sciences. Psychology Genes. Genome Human immunodeficiency virus Humans Infectious diseases Life Sciences Macaca mulatta Macaca rhesus Male Medical sciences Molecular and cellular biology Molecular genetics Molecular Sequence Data Sigma Factor Simian immunodeficiency virus Transcription Factors Viral diseases |
| title | Two alleles for rhesus macaque GPR15 (BOB) |
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