Enantioselective transfer hydrogenation, a key step for the synthesis of 3-aminotetrahydroquinolines

Enantioselective transfer hydrogenation, a key step for the synthesis of 3-aminotetrahydroquinolines

An enantioselective transfer hydrogenation has been successfully achieved to furnish 3-aminotetrahydroquinolines. The reaction was conducted in the presence of Hantzsch dihydropyridine and a catalytic amount of chiral phosphoric acid under mild conditions.

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Veröffentlicht in:New journal of chemistry 2016-01, Vol.40 (11), p.9034-9037
Hauptverfasser: Aillerie, Alexandre, Lemau de Talencé, Vincent, Dumont, Clément, Pellegrini, Sylvain, Capet, Frédéric, Bousquet, Till, Pélinski, Lydie
Format: Artikel
Sprache:eng
Schlagworte:
Catalysis
Chemical Sciences
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Zusammenfassung:An enantioselective transfer hydrogenation has been successfully achieved to furnish 3-aminotetrahydroquinolines. The reaction was conducted in the presence of Hantzsch dihydropyridine and a catalytic amount of chiral phosphoric acid under mild conditions.
ISSN:1144-0546
1369-9261
DOI:10.1039/C6NJ02249A