Laparoscopic versus open subtotal gastrectomy for adenocarcinoma of the stomach in a Western population: peri-operative and 5-year oncological outcomes

Background This study compares the peri-operative and long-term oncological outcomes for laparoscopic subtotal gastrectomy (LSG) versus open subtotal gastrectomy (OSG) for adenocarcinoma of the stomach in a Western population. Methods A retrospective, intention-to-treat analysis study was conducted for consecutive patients undergoing gastrectomy with curative intent for adenocarcinoma of the stomach between November 2006 and October 2016. Univariate analysis was used to compare peri-operative outcomes between LSG and OSG. Logistic regression with bootstrapping validation was used to identify independent risk factors for predicting 2-year overall survival. Results The final analysis included 79 patients. When comparing LSG ( n = 30) to OSG ( n = 49), there was no difference in the number of resected lymph nodes (36 (IQR 24.3–44) vs. 42 (IQR 28–59), p = 0.165), a reduction in intra-operative blood loss (150 ml (IQR 100–250) vs. 553 ml (IQR 338–1075), p