Improvement of the Immunochromatographic NG-Test Carba 5 Assay for the Detection of IMP Variants Previously Undetected

Improvement of the Immunochromatographic NG-Test Carba 5 Assay for the Detection of IMP Variants Previously Undetected

Here, we evaluated the immunochromatographic assay NG-Test Carba 5v2 (NG-Biotech), with improved IMP variant detection on 31 IMP producers, representing the different branches of the IMP phylogeny, including 32 OXA-48, 19 KPC, 12 VIM, 14 NDM, and 13 multiple carbapenemase producers (CPs), 13 CPs tha...

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Veröffentlicht in:Antimicrobial agents and chemotherapy 2020, Vol.64 (1), p.e01940-19
Hauptverfasser: Volland, Hervé, Girlich, Delphine, Laguide, Marine, Gonzalez, Camille, Paris, Virginie, Laroche, Maxime, Oueslati, Saoussen, Dortet, Laurent, Simon, Stéphanie, Naas, Thierry
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Sprache:eng
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Life Sciences
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Zusammenfassung:Here, we evaluated the immunochromatographic assay NG-Test Carba 5v2 (NG-Biotech), with improved IMP variant detection on 31 IMP producers, representing the different branches of the IMP phylogeny, including 32 OXA-48, 19 KPC, 12 VIM, 14 NDM, and 13 multiple carbapenemase producers (CPs), 13 CPs that were not targeted, and 13 carbapenemase-negative isolates. All tested IMP variants were accurately detected without impairing detection of the other carbapenemases.
ISSN:0066-4804
1098-6596
DOI:10.1128/AAC.01940-19