Extracorporeal Membrane Oxygenation for Severe Acute Respiratory Distress Syndrome

This trial compared extracorporeal membrane oxygenation with non-ECMO ventilator care in patients with severe ARDS. There was no significant between-group difference in 60-day mortality. Interpretation was made difficult by crossovers from control to ECMO treatment.

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Bibliographische Detailangaben
Veröffentlicht in:	The New England journal of medicine 2018-05, Vol.378 (21), p.1965-1975
Hauptverfasser:	Combes, Alain, Hajage, David, Capellier, Gilles, Demoule, Alexandre, Lavoué, Sylvain, Guervilly, Christophe, Da Silva, Daniel, Zafrani, Lara, Tirot, Patrice, Veber, Benoit, Maury, Eric, Levy, Bruno, Cohen, Yves, Richard, Christian, Kalfon, Pierre, Bouadma, Lila, Mehdaoui, Hossein, Beduneau, Gaëtan, Lebreton, Guillaume, Brochard, Laurent, Ferguson, Niall D, Fan, Eddy, Slutsky, Arthur S, Brodie, Daniel, Mercat, Alain
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Blood pressure Carbon dioxide Critical care Cross-Over Studies Extracorporeal membrane oxygenation Extracorporeal Membrane Oxygenation - adverse effects Female Hemorrhage - etiology Hospitals Humans Hypoxemia Hypoxia Ischemia Kaplan-Meier Estimate Life Sciences Male Mechanical ventilation Medicine Middle Aged Mortality Nutrition Oxygen Oxygenation Patients Physiology Respiration, Artificial - adverse effects Respiratory distress syndrome Respiratory Distress Syndrome - mortality Respiratory Distress Syndrome - therapy Respiratory therapy Severity of Illness Index Stroke Thrombocytopenia Thrombocytopenia - etiology Treatment Outcome Ventilators
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Beschreibung
Zusammenfassung:	This trial compared extracorporeal membrane oxygenation with non-ECMO ventilator care in patients with severe ARDS. There was no significant between-group difference in 60-day mortality. Interpretation was made difficult by crossovers from control to ECMO treatment.
ISSN:	0028-4793 1533-4406
DOI:	10.1056/NEJMoa1800385